Lipid-Altering Drugs
نویسندگان
چکیده
منابع مشابه
Lipid-Altering Drugs: Decreasing Cardiovascular Disease at the Expense of Increasing Cancer?
To the Editor: The interesting paper by Cao et al. (1) exposes a disturbing paradox in preventive medicine that has significant implications. They demonstrated that expression of a mutant receptor for high-density lipoprotein (HDL) on breast cancer cell line MCF-7 inhibited the proliferation and attenuated the antiapoptotic effect of HDL on the breast cancer cells. This supports previous data s...
متن کاملLipid-altering drugs: decreasing cardiovascular disease at the expense of increasing cancer?
To the Editor: The interesting paper by Cao et al. (1) exposes a disturbing paradox in preventive medicine that has significant implications. They demonstrated that expression of a mutant receptor for high-density lipoprotein (HDL) on breast cancer cell line MCF-7 inhibited the proliferation and attenuated the antiapoptotic effect of HDL on the breast cancer cells. This supports previous data s...
متن کاملHepatotoxic Effects of Lipid-altering Agents
Dyslipidemia is a major risk factor for coronary heart disease (CHD), and current guidelines support low-density lipoprotein cholesterol (LDL-C) as a primary target of therapy.[1] Previous studies suggest that increasing high-density lipoprotein cholesterol (HDL-C) and reducing triglycerides and small LDL particles may also have a positive impact in prevention.[2] These factors are considered s...
متن کاملLipid lowering drugs.
likelv that L donovani was of animal origin, as were other members of the genus, and in Brazil, foxes are a significant animal reservoir. The sensitivity of the Brazilian disease to antimonial drugs does not fit with the resistance of the infantum subspecies found in Portugal. Today there are epidemics of kala-azar among poor children in favelas in cities of north eastern Brazil such as Teresin...
متن کاملDrugs and lipid metabolism.
I propose to give a review of the effect of drugs on lipid metabolism which will be extensive rather than intensive. Several excellent reviews are available that discuss the drugs which are most effective for lowering plasma lipid levels in the six main types of human hyperlipoproteinaemia (Lees & Wilson, 1971 ; British Medical Journal, I 972 ; Levy, Fredrickson, Shulman, Bilheimer, Breslow, St...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2004
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-04-1017